Masha Anti Acne Treatment 100 ml Masha Anti Acne begins by eliminating skin impurities upon application. It helps prevent the appearance of new impurities. For acne-prone skin with stubborn breakouts, Masha Anti Acne can be used all over the face or as a spot treatment. Instructions for use: In the evening before going to bed, place a few drops in the palm of your hand and gently massage the skin on your face.